Monthly Archives: August 2014

New capabilities for the 3Flex – simultaneous analysis of three samples each using a different adsorptive

The Micromeritics 3Flex design includes metal seals, hard seal valves, and both a Pirani and cold cathode vacuum gauges.  The hardware is complemented by the state of the art software which continuously monitors  the status of the instrument.  These hardware and software feautures allow 3Flex users to perform adsorption experiments that were previously unavailable in multi-port instruments.  3Flex users may characterize three samples simultaneously and each sample may use a different adsorptive.   Continue reading

The Utility of Specific Surface Area Measurement for Pharmaceutical Materials

Myke Scoggins | Senior Pharmaceutical Scientist | Micromeritics Instrument Corporation

In the pharmaceutical world, particle size analysis has traditionally been the method of choice to “characterize” raw materials.  Beginning with sieve analyses all the way to more current technologies like laser light scattering, this physical characterization measurement has been used to set incoming raw material specifications, help determine which excipients will be used in a formulation, and troubleshoot product performance issues such as dissolution.  While particle size analysis is, without a doubt, an important piece of the puzzle, it is exactly that – a piece.  Other measurements can provide essential and useful information as well and, when paired with other techniques, assist the pharmaceutical scientist to more fully characterize their Active Pharmaceutical Ingredients (API) and excipient materials.  Among these techniques is the measurement of surface area. Continue reading